Clinical research & methodology

Research that survives peer review.

Study design, advanced statistical analysis, systematic reviews and manuscript support — delivered by medical doctors who publish, with every result independently verified and reproducible from raw data to final table.

No obligation · Sun–Thu, 09:00–18:00 GMT+2 · We work worldwide

Three factors that make a research institution reliable

  1. 01 A research-active medical team Every member: 50+ publications, h-index ≥ 5. Researchers, not only clinicians.
  2. 02 A proven track record at scale 1,000+ researchers supported across 5,000+ projects, spanning every specialty and study design.
  3. 03 Structured quality control Data checks, appropriate methodology, independent review and reproducible practice before anything is delivered.

Reliability isn't a claim. It's a process you can ask to see.

1,000+
Researchers and clients supported
5,000+
Research projects delivered
50+
Publications per team member, minimum
18
Advanced method families in daily use

Every ClinStat team member is a practising medical doctor with an active research record — a minimum of 50 scientific publications and an h-index of 5 or higher.

The standard

What actually makes a research finding “reliable”?

Not a vibe — a checklist. Eight checks run on every project, before the result is allowed to become a conclusion.

  • High-quality, validated data
  • A design and sample size that can answer the question
  • A statistical analysis matched to the design
  • Model assumptions formally tested
  • Sensitivity and robustness analyses
  • Missing data addressed, not deleted
  • Independent verification by a second statistician
  • Full reproducibility from raw data to final table
  1. A highly qualified, research-active medical team

    Our team is made up of medical doctors actively involved in scientific research — every member has at least 50 scientific publications and an h-index of 5 or higher. That means sustained, current experience in research methodology, scientific writing, peer review and academic publishing, not clinical expertise alone.

  2. Extensive experience and a proven track record

    More than 1,000 researchers and clients supported across over 5,000 research projects, spanning different specialties, study designs and stages of the research process. A portfolio that size is what produces judgement about complex research questions, statistical analyses, systematic reviews, manuscripts and publication problems.

  3. Real quality-control and research infrastructure

    Reliable research takes more than individual expertise. We run a structured workflow with data-quality checks, appropriate statistical methodology, independent review of every analysis, reproducible research practices and scientific quality assurance before anything is delivered.

Methodological depth

If your project touches any of these, it is exactly our specialty — not a side skill.

18 advanced method families our team works with routinely. Each one is the difference between an analysis that looks correct and one that is.

Propensity scores, IPTW & doubly robust estimation

Comparing groups that were never randomised, without pretending confounding away.

Longitudinal & repeated-measures modelling

Measurements taken from the same patient are not independent — and analysing them as if they were inflates significance.

Survival & competing-risk analysis

Time-to-event data is not about death. It is about when anything happens — and what else could have happened first.

Missing-data methodology

Deleting every patient with a gap is a decision about your results, not a neutral default.

Advanced, network, IPD & diagnostic meta-analysis

Pooling is the easy part. Heterogeneity, transitivity and inconsistency are where reviews are won or lost.

Prediction model development, validation & machine learning

A model that discriminates well and calibrates badly will still give the wrong answer to a real patient.

Multiplicity & false discovery control

Test twenty outcomes at the 5% level and one will look significant by construction.

Sensitivity & robustness analysis

A finding that only exists under one set of analytical choices is not a finding.

Mediation & moderation analysis

Not just whether an exposure works — through what, and for whom.

Also in routine use

Non-linear modelling & restricted cubic splinesSample-size & power estimationBayesian statisticsHeterogeneity of treatment effectsSubgroup & interaction analysisIndependent verification & reproducible analysisIndividual participant data (IPD) meta-analysisDiagnostic test accuracy meta-analysisMachine learning in clinical research

How a project runs

Every project we take on follows the same path.

A process built for accuracy. Results built for impact.

  1. UnderstandA free 15-minute call to establish the research question, what data exist, and what the deadline really is.
  2. PlanDesign review or a written statistical analysis plan tied to the question — agreed before any modelling begins.
  3. ValidateStructured data validation: ranges, logic, duplicates, coding harmonisation, eligibility and missingness, with an audit trail.
  4. AnalyseThe analysis the question requires, with assumptions tested and sensitivity analyses run, in reproducible code.
  5. VerifyA second statistician independently reproduces every primary result from the cleaned dataset.
  6. DeliverPublication-ready tables, figures, methods and results text — plus the scripts, so every number is traceable.

Free resource

Before you submit — check it against this.

Most desk rejections come down to the same avoidable gaps. This is the 12-point checklist our team runs internally before any manuscript goes out. It takes about ten minutes, and it is completely free.

The three that end most papers early

Statistical reporting gaps Effect sizes without intervals; methods that don't match results.
Incomplete ethics documentation No committee named, no reference, no consent statement.
Unclear authorship Contributions, conflicts and funding left vague.

All three are avoidable with one structured review before submission — not after rejection.

Trusted by researchers worldwide

A few words from those we work with.

“Professional, detail-oriented, scientifically rigorous and true to success at every step of our research.”
Principal InvestigatorCardiology
“Exceptional expertise and support throughout the entire process.”
ResearcherOncology
“They turned a complex problem into clear answers we could actually use.”
AcademicPublic Health
“They clarified everything. The results speak for themselves.”
InvestigatorNeurology
“Our go-to team for biostatistics and study design.”
ResearcherPharmacology

Questions

The things researchers ask us first.

All questions and answers

Let’s make your next result defensible.

Book a free 15-minute consultation. Tell us the research question, the data you have, and the deadline — we will tell you honestly what is achievable.

Or call +20 100 163 8864 · Sunday–Thursday, 09:00–18:00 (GMT+2, Cairo)

WhatsApp us